Since the source data can be updated at any time while the Brief Profiles are updated at intervals, a slight delay in the publication of information may occur. Related Topics . The Agency does not take any responsibility whatsoever for any copyright or other infringements that may be caused by using the information. Please note: The icons in this section are only meant as visual indicators to help communicate information about the abovementioned critical properties. This section provides ecotoxicological information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The EC name and number are the official identifiers for substances within the European Union and can be found in the EC Inventory. The ‘Properties of concern’ section shows ECHA-assigned graphical indicators for certain substance properties that are regarded as critical for human health and/or the environment based on the information provided to the Agency. Half-life in soil provides substance information on the substance’s half-life in water in seconds/minutes/hours/days/weeks/months/years at a temperature measured in °C. The availability of additional data beyond the five results displayed is indicated by (…). The purpose of the information provided under this section is to highlight in a readable format the substance hazardousness. This section summarises the flash point values from all registered dossiers for the substance. Data from all dossiers registered for the same substance is used in the summarisation and aggregation process, as it is presumed that all data submitted by the registrants is relevant for the substance being registered. Data is generally displayed in milligram per kilo bodyweight. Registration, Evaluation, Authorisation and Restriction of Chemicals (REACH)The REACH Regulation (1907/2006) entered into force on 1 June 2007. Long-term EC10 or LC10 or NOEC for terrestrial plants provides substance information on the substance’s effect concentration or lethal concentration (long term) for 10% of the terrestrial plants in the test, or the no observed effect concentration for terrestrial plants. If the substance has no EC number attributed, ECHA will attribute a list number. Note: Registrants can also select ‘BMD’, ‘BMC’, ‘dose level’ and ‘conc. Short-term EC50 or LC50 for soil microorganisms provides substance information on the substance’s effect concentration or lethal concentration (short term) for 50% of soil microorganisms in the test, generally displayed in milligram per kilo soil (dry weight). Note: Registrants can also select ‘other’ as the type of Henry’s law constant. a= 15.7) can still be used Note; The pK. Immediately call a poison center or doctor/physician. Sodium hydride (NaH), when used with certain solvents, can unexpectedly generate heat and gas, leading to a runaway reaction or even an explosion (Org. This section displays the values related to immunotoxicity from all registered dossiers for the substance. Data is generally displayed in milligrams per kilogram, per bodyweight per day. Values are generally displayed in milligrams per kilogram (dry weight). If the substance is classified under more than one CLH entry (e.g. 1.6), oxidising: maximum burning rate equal or higher than reference mixture, oxidising: vigorous reaction in preliminary test. This section summarises the dissociating values from all registered dossiers for the substance. Displayed are the RANGES of min – max of values (provided in %). By summarising the endpoint study data, ECHA aims to make this information accessible in a user-friendly way in line with the Agency’s goals and standards. Though the Agency aims to include as many studies as possible in the Brief Profile endpoint study results/summaries, those studies which do not fit the format or miss crucial information (such as measurement conditions) cannot be processed and therefore will not be included on this page. Dermal route provides substance information on the substance’s acute toxicity via the dermal route. EC10 / LC10 or NOEC for marine sediment provides substance information on the substance’s effect concentration/lethal concentration for 10% of the model organisms feeding off the marine sediment or the no observed effect concentration for of the model organisms feeding off the marine sediment. Since a two dimensional chemical structure can be drawn in various ways, there are several correct SMILES notations for one molecule. This section summarises the values related to long term toxicity to aquatic invertebrates from all registered dossiers for the substance. A reagent that, in a reaction, acts as the hydride ion would if it were nucleophilic is called a hydride reagent or hydride equivalent. The quality and correctness of the information remains the responsibility of the data submitter. Please note that when more than one summary is provided, DN(M)EL values may refer to constituents of the substance and not to the substance as a whole. SODIUM HYDRIDE is a powerful reducing agent. The date of the last update corresponds to the publication date of the Brief Profile and not necessarily to the date in which the update occurred in the source data (registered dossiers, the C&L Inventory or a regulatory process). More information on processable studies and data-waiving is available in the section help of the ‘Scientific properties’ header. 1.3), Very insensitive substances with mass explosion hazard (Div. Values are generally displayed in measured in (nano/ micro/milli)gram per kilogram (dry weight). Why you are interested in this job in Hawkins company? Long-term EC10 or LC10 or NOEC for soil microorganisms provides substance information on the substance’s effect concentration or lethal concentration (long term) for 10% of the soil microorganisms in the test, or the no observed effect concentration for soil microorganisms. Water solubility provides substance information on the substance’s solubility in water in grams per litre at a temperature measured in °C. Who is the longest reigning WWE Champion of all time? This section displays the values related to reproductive toxicity from all registered dossiers for the substance. AlzChem Trostberg GmbH, Dr.-Albert-Frank-Straße 32 83308 Trostberg Bayern Germany, AZOINTERNATIONAL OU, RAUA 28 10152 TALLINN Estonia, Chr. More detailed information is available in the dossiers. And so one way to figure out which direction is favored is to use these equations down here. EC50/LC50 for marine water plants provides substance information on the substance’s effect concentration or lethal concentration for 50% of the marine water algae in the test, generally displayed in milligram per litre. BOD5*100/COD provides substance information on the substance’s BOD5*100/COD values displayed in O2 (milli)gram per gram test material. Processable data for study results is prioritised by endpoint conclusion: the most conservative value is displayed. For this endpoint registrants do not provide summary data. The % is based on count of values provided. Displayed is the MOST CONSERVATIVE of the value(s) provided, ranking in the order as below. Remove contact lenses if present and easy to do – continue rinsing. Short-term EC50 or LC50 for birds provides substance information on the substance’s effect concentration or lethal concentration (short term) for 50% of birds in the test, generally displayed in milligram per kilo food. This section summarises the boiling point values from all registered dossiers for the substance. Dissociating Properties provides substance information by picklist values: Dissociation Constant provides numerical substance information on the substance’s dissociation constant values at a temperature measured in °C. More detailed information is available in the dossiers. Results without measurement conditions (pressure) are not processed for the Brief Profile. This section summarises the Ecotoxicological information provided from all registered dossiers for the substance. Expensive dry strong bases commonly chosen include sodium methoxide (methylate), potassium t-butoxide, sodium amide, sodium hydride, sodium metal, LDA or others. EC10 / LC10 or NOEC for freshwater plants provides substance information on the substance’s effect concentration/lethal concentration for 10% of the tested freshwater plants or the no observed effect concentration for freshwater plants. This section summarises the values related to hydrolysis from all registered dossiers for the substance. Half-life for hydrolysis provides substance information on the substance’s half-life for hydrolysis in seconds/minutes/hours/days/weeks/months/years at a temperature measured in °C.Note: Results without a measurement condition (temperature) are not processed for the Brief Profile. List of substances subject to the POPs Regulation - Indicates if the substance is included in the POPs Regulation. This section summarises the values related to toxicity to birds from all registered dossiers for the substance. Values are generally displayed in milligram per litre. If more than one numerical result is available per endpoint, the range of results (min–max) and range of experimental conditions will be presented (RANGE method). If so, the data provided is not processed in the Brief Profile. Home. When more than one summary is provided, DN(M)EL values may refer to constituents of the substance and not to the substance as a whole. How long will the footprints on the moon last? The light blue bar illustrates the percentage of matching substance classifications provided by manufacturers and importers in CLP notifications. When did organ music become associated with baseball? Data is generally displayed in milligrams per kilogram in the case of soil (dry/wet weight) or gram per hectare. Y is the check-digit calculated in accordance with the 10-digit ISBN method. In case of fire: Use (measures specified by manufacturer/supplier) for extinction. Data is generally displayed in milligrams per kilogram in the case of soil (dry/wet weight), or gram per hectare. Sodium borohydride (NaBH4) decomposes rapidly in water (especially if acidic). H atm provides substance information on the substance’s Henry’s Law Constant in atm at temperature measured in °C and a pressure measured in Pascal. Note: Registrants can also select ‘BMD’, ‘BMC’, ‘dose level’ and ‘conc. The IUPAC nomenclature is a systematic way of naming chemical substances, both organic and inorganic. Do not induce vomiting. This section searches three sources for information (harmonised classification and labelling (CLH), REACH registrations and CLP notifications). Oxidation reduction potential in mV at 20°C provides substance information on the substance’s oxidation reduction measured in millivolts at a temperature of 20°C. Classifications under REACH have to be supported by data (support studies). If on skin: Brush off loose particles from skin. If more than one type of substance is registered, both types will be displayed. Reacts … Otherwise data is displayed reported as provided by the registrant(s).The availability of additional data beyond the five results displayed is indicated by (…). The Brief Profile is produced based on data in ECHA’s databases and maintained by the Agency, and therefore the Brief Profile as a dissemination tool falls under ECHA’s responsibility. . Degradation rate constant (OH Radicals) provides substance information on the substance’s degradation rate constant with OH Radicals as a reaction type in cm3molecule-1s-1, cm3molecule-1d-1, m3molecule-1s-1 or m3molecule-1d-1. Values are generally displayed in milligram per kilo soil (dry weight). If the reactant or product is very sensitive to nucleophiles (reactants such as phosgene, acyl chlorides, sulfonyl chlorides, phosphoryl chlorides, anhydrides, epoxides), then bases such as NaH or sodium metal are often chosen. The EC Inventory is a combination of three independent European lists of substances from the previous EU chemicals regulatory frameworks (EINECS, ELINCS and the NLP-list). Biodegradation in water - screening tests, Biodegradation in water & sediment - simulation tests. Phototransformation in soil provides substance information on the substance’s phototransformation in soil in seconds/minutes/hours/days/weeks/months/years. H atm m3/mol provides substance information on the substance’s Henry’s Law Constant in atm m3/mol at a temperature measured in °C and a pressure measured in Pascal. This section summarises the values related to toxicity to sediment toxicity from all registered dossiers for the substance. This section summarises the values related to terrestrial bioaccumulation in all registered dossiers for the substance. pH provides substance information on the substance’s acidity level measured in pH at a temperature measured in °C and a concentration measured in (milli)grams per litre. Registrants can choose from the following picklist endpoint conclusions/effect levels: Eye irritation provides substance information on the substance’s irritation effect on the eye. If a substance is classified under multiple CLHs, a link to the C&L Inventory is provided to allow users to view CLH information manually, instead of having the information automatically generated in the Brief Profile. Data is generally displayed in milligrams per kilogram bodyweight per day. Processable data is prioritised by the toxicity descriptor type (see list below) and subsequently further prioritised by duration (longer prioritised over shorter). level’ as the dose descriptor. Processable data is prioritised by the toxicity descriptor type (see list below) and subsequently further prioritised by duration (longer prioritised over shorter). ThOD provides substance information on the substance’s ThOD values displayed in O2 (milli)gram per gram test material. What are the ratings and certificates for The Wonder Pets - 2006 Save the Nutcracker? Sodium Hydride 60 % in mineral oil. No data available: testing technically not feasible. This section provides environmental fate and pathways information compiled from all registered dossiers for the substance. In practice, however, the hydride ion is strongly basic but not nucleophilic. Attacks SiO2 in glass. H dimensionless volumetric basis provides substance information on the substance’s Henry’s Law Constant in dimensionless volumetric basis at a temperature measured in °C and a pressure measured in Pascal. EC10 / LC10 or NOEC for marine fish provides substance information on the substance’s effect concentration/lethal concentration for 10% of the tested freshwater fish or the no observed effect concentration. Applicant’s summary and conclusion – Interpretation of results. Shipping Name: SODIUM BOROHYDRIDE SODIUM BOROHYDRIDE Hazard Class: 4.3 4.3 UN Number: UN1426 UN1426 Packing Group: I I Section 15 - Regulatory Information US FEDERAL TSCA CAS# 16940-66-2 is listed on the TSCA inventory. 1.2), Fire and minor blast and/or projection hazard, but not a mass explosion hazard (Div. 4 - Complete the equation for the reaction between... Ch. This section summarises the values related to toxicity to (terrestrial) plants from all registered dossiers for the substance. Displayed are the RANGES of min – max of the PRIORITISED value(s) within the five highest priority groupings of provided data. EC10 / LC10 or NOEC for freshwater sediment provides substance information on the substance’s effect concentration/lethal concentration for 10% of the model organisms feeding off the freshwater sediment or the no observed effect concentration for of the model organisms feeding off the freshwater sediment. This section displays the values (see below) related to toxicokinetics, metabolism, and distribution from all registered dossiers for the substance. COD provides substance information on the substance’s COD values displayed in O2 (milli)gram per gram test material. Short-term EC50 or LC50 for soil dwelling arthropods provides substance information on the substance’s effect concentration or lethal concentration (short term) for 50% of the soil dwelling arthropods in the test, generally displayed in milligram per kilo soil (dry weight). These study results can however be consulted when opening the source data. This section summarises the values related to endocrine disrupter testing in aquatic vertebrates from all registered dossiers for the substance. The CLP regulatory processes identified for the Brief Profile are: The BPR (528/2012) entered into force on 1 September 2013. Data for calculating the ’total tonnage’ band is extracted from REACH registered dossiers for the last year reported on the tonnage manufactured or imported, unless the tonnage band has been claimed confidential. Translated names gives the names in different EU languages, where available to ECHA. Pre-registration allows companies to continue manufacturing and importing their. This section summarises the values related to toxicity to aquatic plants (other than algae) from all registered dossiers for the substance. For readability purposes, only the pictograms, signal words and hazard statements referred to in more than 5% of the notifications under CLP are displayed. Data for workers – eye exposure provides information on the substance’s hazard assessment conclusions regarding eye exposure (for workers). Using pKa values given in Table 4.1, calculate Keq for this equilibrium. 4 - Using pKa values given in Table 4.1, predict the... Ch. IUPAC names gives all the non-confidential names provided to ECHA in submissions under REACH, CLP, BPR and PIC, where indicated to be a IUPAC name. 2(b)(i) - Hazardous Agents, EU Ecolabels - Restrictions for Hazardous Substances/Mixtures, Workplace Signs - minimum requirements & signs on containers and pipes, Waste Framework Directive, Annex III - Waste - Hazardous Properties, Sodium Hydride (60%, dispersion in Paraffin Liquid), EC Inventory, C&L Inventory, Registration dossier, REACH pre-registration, Other, CAD - Chemical Agents Directive, Art. Henry’s Law Constant provides substance information on the substance’s Henry’s Law Constant measured in in Pa.m3.mol-1 at a temperature measured in °C. If so, the data provided is not processed for the Brief Profile. Bulk density provides substance information on the bulk density in (kilo)grams per (centi)metre (cm/m) at a temperature measured in °C. Short-term EC50 or LC50 for mammals provides substance information on the substance’s effect concentration or lethal concentration (short term) for 50% of mammals in the test, generally displayed in milligram per kilo food. Processable data for study results is prioritised by dose descriptor type (see list below) and subsequently further prioritised by the test species. If no data is available in the registered substance dossiers, this will be indicated by a notification stating ‘Data not provided by the registrant’. The number of studies provided is indicated by ‘[x] studies submitted’, while the actual number of studies processed for the endpoint is indicated by ‘[x] studies processed’. Values are generally displayed in milligram per kilo soil (dry weight). Praesent et nulla orci. BOD5/ThOD ratio provides substance information on the substance’s BOD5/ThOD ratio values displayed in O2 (milli)gram per gram test material. The source of the information is mentioned in the introductory sentence of the hazard statement. Registrants can register their substance’s bioaccumulation properties as: Registrants can register their substance’s oral/dermal/inhalation absorption rate values in percentages. Data is generally displayed in milligram per litre air. Displayed are the RANGES of min – max of the PRIORITISED value(s) within the five highest priority groupings of provided data. Depending on the structure of the molecule the main layer may be followed by additional layers e.g. Booster Classes. PIC administers the import and export of certain hazardous chemicals and places obligations on companies who wish to export these chemicals to non-EU countries. If one adds sufficient sodium hydroxide, NaOH, to a solution of acetic acid in water then the hydroxide anion will totally deprotonate the acetic acid, because the hydroxide ion is a strong base in water. Displayed are the RANGES of min – max of the PRIORITISED value(s) within the five highest priority groupings of provided data. Other identifiers gives any other non-name identifiers available for ths substance. If inhaled: remove victim to fresh air and keep at rest in a position comfortable for breathing. 4 - For each equation, label the Lewis acid and the... Ch. Acetylene + Sodium Hydride ---> Sodium Acetylide + Hydrogen The aim is to display the lowest values reported as causing the most adverse effects, and hence the broadest possible safety margins for the substance. The conjugate acid is Hydrogen (H2), the pKa of which is 35. Water solubility provides substance information on the substance’s solubility in water in grams per litre at a temperature measured in °C. Pow provides substance information on the partition coefficient type Pow at a temperature measured in °C and acidity in pH. For a detailed overview on identified uses and environmental releases, please consult the detailed information from the registration dossiers. LC50 for marine water fish provides substance information on the substance’s lethal concentration for 50% of the marine water fish in the test, displayed in milligram per litre. However, substance notifications in the Brief Profile are aggregated independently of the impurities and additives. Melting / freezing point provides substance information on the melting/freezing point in °C at a pressure measured in Pa. ECHA maintains the C&L Inventory, but does not review or verify the accuracy of the information. Solubility in organic solvents / fat solubility. For substance’s physical state at 20°C and 1013 hPa, registrants can classify their substance as: This section provides an overview of the type of study records behind the presented results and – if applicable - data–waving justifications. 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Paraffin Liquid ) C & L ) – indicates if the substance an industrial use resulting in manufacture:. The list of substances subject to pic Elizabeth Berkley get a gap between her teeth! Freezing point values from all registered dossiers for the substance other above-ground organisms ) from all dossiers... Between her front teeth of any other authority truce in the Brief Profile are: icons!
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